About EPI

EPI is associated with a number of conditions4,5

EPI is characterized by deficiencies in the amount or activity of exocrine pancreatic enzymes. This can result in the inability to digest food properly, or maidigestion.2,4-6

Conditions where EPI could be an important factor3,5,6

  • Cystic fibrosis (CF)
  • Chronic pancreatitis
  • GI and pancreatic surgical procedures
  • Diabetes (Type 1 and Type 2)
  • Pancreatic cancer tumors

Signs/Symptoms of Maldigestion or Malabsorption associated with EPI2,6

  • Steatorrhea, abdominal pain, bloating, flatulence, or weight loss
  • Stool symptoms: frequent, soft, watery, bulky, oily, foul-smelling, or diarrhea

Because the signs and symptoms of EPI are similar to those of other GI diseases. EPI may go undetected.7

Goals and management of EPI

In addition to the treatment of causative factors, there are 2 key goals for managing EPI.5,7-10

Improving digestion and absorption of nutrients

Relieving GI signs and symptoms of EPI

Managing EPI includes...5,7-10

Lifestyle and dietary modifications

Vitamin and nutrient supplementation

Pancreatic enzyme therapy